Oct '21
MCAT Question of the Day

  • Q:

    A bacterium has been genetically transformed with human Gene A which consists of approximately 800 nucleotides. During expression, researchers notice that the protein is not being translated; only fragments of approximately 50 amino acids are formed. Genetic sequencing shows there are no nonsense mutations in the gene sequence. Which of the following is a plausible explanation for the observation?



    The bacterium lacks the tRNA that corresponds to the particular codon for the 51st amino acid.


    The bacterial ribosome is incompatible with the human mRNA and cannot properly translate the protein.


    The bacterium is unable to glycosylate the protein, terminating translation early.


    The human gene is too long; bacteria can only synthesize proteins up to approximately 50 amino acids.

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